Product Introduction

Trehalose is a typical stress metabolite that forms a unique protective layer on the cell surface under harsh environmental conditions such as high temperature, extreme cold, high osmotic pressure, and dehydration. This effectively protects the structure of biological molecules, thereby maintaining the life processes and biological characteristics of the organism.

Trehalose, also known as mycose or mushroom sugar, is a non-reducing disaccharide composed of two glucose molecules with the molecular formula C12H22O11. The structure of trehalose is α-D-glucopyranosyl-α-D-glucopyranoside, often found as a dihydrate with the molecular formula C12H22O11·2H2O.

It is widely present in various organisms, including bacteria, yeast, fungi, algae, and some insects, invertebrates, and plants, particularly in yeast. Trehalose is also found in fermented foods like bread and beer, as well as in shrimp. α,β-type and β,β-type trehalose are rare in nature, found in small amounts in honey and royal jelly. These two types can be chemically synthesized.

Trehalose is a growth factor for beneficial intestinal bacteria, such as bifidobacteria, improving gut microbiota, enhancing gastrointestinal digestion and absorption, effectively eliminating toxins, and boosting the body's immune response. Research also shows that trehalose has strong anti-radiation properties.

Production Process

The goal of trehalose production is to obtain high-purity trehalose products and related enzyme products. There are three main methods for preparing trehalose in the lab and production:

  1. Extraction from biological cells;
  2. Microbial fermentation production;
  3. Enzyme synthesis of trehalose using enzymes extracted from microbial fermentation.

Fermentation Method: Due to the rapid growth and reproduction of microorganisms, which are easy to cultivate, deep fermentation of trehalose has inherent advantages. Yeast and bacteria that produce trehalose are selected and cultured for high-yield strains, then fermented to produce trehalose. Effective separation and extraction methods are then used for refinement.

Enzyme Synthesis Method: Enzyme synthesis uses enzymes produced and extracted through microbial fermentation to synthesize trehalose from various carbohydrates. The main challenge with enzymes is their fragility and tendency to deactivate. In actual production, maintaining enzyme activity and managing enzyme preparation costs are crucial, with enzyme immobilization or cell immobilization techniques being used to protect the enzymes.

Benefits and Functions

Trehalose is a naturally occurring disaccharide that serves as an energy source for many organisms.

It is stable under heat and acidic or alkaline conditions, making it safe for human health. Trehalose is commonly used in foods and health products that require high heat processing and preservation, as well as in products like lip balms and mouthwashes.

In addition, trehalose has moisturizing and sunscreen properties, making it a common ingredient in cosmetics such as lotions and facial cleansers. In the pharmaceutical industry, trehalose is primarily used as a filler and taste-masking agent.

Trehalose is not an artificial sweetener. It is a naturally occurring non-reducing disaccharide.

Trehalose is absorbed in the small intestine and broken down into two glucose molecules, providing essential energy for metabolism and daily activities.

Food Applications: Health Foods, Foods, Pharmaceuticals, Beauty Products

  1. Food Industry

In the food industry, trehalose is being researched for various applications due to its non-reducing nature, moisturizing properties, anti-freezing, and drying resistance, superior sweetness, and energy source. Trehalose can be used in various foods and seasonings, significantly improving food quality, increasing product variety, and promoting further development of the food industry.

Functional Properties and Applications in Food:

(1) Prevents starch aging

(2) Prevents protein denaturation

(3) Inhibits lipid oxidation and spoilage

(4) Flavor enhancement

(5) Maintains the stability and freshness of vegetables and meats

(6) Provides a long-lasting, stable energy source

  1. Pharmaceutical Industry

In the pharmaceutical industry, trehalose is used as a stabilizer for reagents and diagnostic agents. Its non-reducing nature, stability, protective effects on biological macromolecules, and energy provision make it versatile. Drying antibodies such as vaccines, globulins, viruses, and other biologically active substances with trehalose can restore activity without freezing. Trehalose also serves as a stabilizer in biological products, preventing contamination and ensuring the preservation, transportation, and safety of biological products at room temperature.

  1. Cosmetics

Trehalose's strong moisturizing and sun-protective properties make it useful as a moisturizing agent and protective agent in lotions, masks, serums, and facial cleansers. It is also used as a sweetener and quality enhancer in lip balms, oral cleansers, and breath fresheners. Anhydrous trehalose can be used in cosmetics as a dehydrating agent for phospholipids and enzymes, and its fatty acid derivatives serve as excellent surfactants.

  1. Crop Breeding

Through biotechnology, trehalose synthase genes can be introduced into crops to create transgenic plants capable of producing trehalose. This breeding technique results in new varieties of frost- and drought-resistant transgenic plants, improving crop resilience while maintaining their original flavor and texture after harvest.

Trehalose can also be used in seed preservation, effectively maintaining moisture in seeds and seedlings, facilitating planting with higher survival rates, and protecting crops from cold damage. This is particularly important for reducing production costs in regions with cold, dry climates, like northern areas.

Packaging and Storage

Storage Conditions: Store in a sealed, light-blocking, cool, dry, and well-ventilated place

Packaging: 25kg/fiber drum for bulk, 1kg/aluminum foil bag for samples; custom packaging available upon request

Shipping: Courier or logistics, domestic courier delivery within three days, logistics within five days. Prices generally include domestic shipping

Shelf Life: Two years

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